Abstract #0939
MRS-based vertebral bone marrow fat quantification using prior fat spectrum characterization and T2 correction
Michael Dieckmeyer 1 , Stefan Ruschke 1 , Christian Cordes 1 , Samuel Paran Yap 1 , Hendrik Kooijman 2 , Hans Hauner 1 , Ernst J. Rummeny 1 , Jan S. Bauer 1 , Thomas Baum 1 , and Dimitrios C. Karampinos 1
1
Technische Universitt Mnchen, Munich,
Germany,
2
Philips
Healthcare, Germany
MRS-based vertebral bone marrow fat quantification is
confounded by the overlapping of water and fat peaks and
the differences in T
2
relaxation
times of water and fat. The purpose of the present study
was to determine using single-voxel MRS the vertebral
bone marrow proton density fat fraction (PDFF) using
single-voxel MRS, addressing the confounding effects
introduced by overlapping water-fat peaks and the
difference in T
2
relaxation
time between the water and fat components. The
importance of the consideration of T
2
decay
effects in bone marrow fat quantification was shown in
the context of the analysis of the bone marrow fat
fraction age dependence.
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