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Abstract #1052

Low dynamic mechanical tissue stimulation for high resolution magnetic resonance elastography: An in vivo feasibility study in the liver and the brain

Florian Dittmann 1 , Sebastian Hirsch 1 , Jing Guo 1 , Jrgen Braun 2 , and Ingolf Sack 1

1 Institute of Radiology, Charit, Berlin, Germany, 2 Department of Medical Informatics, Charit, Berlin, Germany

We propose a MRE method utilizing shear waves induced by continuous low frequency vibration (10 20 Hz). The method is demonstrated for high resolution elastography of the brain and liver, and compared to results obtained by standard MRE frequencies from 25 to 50 Hz. Through low attenuation of the waves, a homogenous illumination of the tissue is achieved and high resolution elastograms are reconstructed despite long wave lengths. This opens the possibility to investigate tissue behavior with low dynamic MRE e.g. for exploiting poroelastic tissue properties.

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