Abstract #1109
Relaxation along fictitious field, diffusion weighted imaging, and T 2 mapping of prostate cancer: correlation of quantitative values with Gleason score
Ivan Jambor 1 , Marko Pesola 1 , Harri Merisaari 2 , Pekka Taimen 3 , Peter J Bostrm 4 , Timo Liimatainen 5 , and Hannu J Aronen 1
1
Department of Diagnostic Radiology,
University of Turku, Turku, Finland,
2
Turku
PET Centre, University of Turku, Turku, Finland,
3
Department
of Pathology, Turku University Hospital, Turku, Finland,
4
Department
of Urology, Turku University Hospital, Turku, Finland,
5
Department
of Biotechnology and Molecular Medicine, A.I. Virtanen
Institute for Molecular Sciences, University of Eastern
Finland, Kuopio, Finland
Fifth-one patients with histologically confirmed PCa
underwent 3T MRI consisting of relaxation along
fictitious field (RAFF), diffusion weighted imaging (DWI),
b valeus of 0, 100, 300, and 500 s/mm
2
, and T
2
mapping.
Using whole mount prostatectomy sections and anatomical
T
2
-weighted images as reference, one ROI was
placed in the center of PCa area and the same sized ROI
in the peripheral zone, and central gland not containing
PCa. High spearman correlation coefficient value of
-0.68 was found for correlation of RAFF relaxation
values with Gleason score groups, outperforming DWI (ADC
m
)
and T
2
mapping.
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