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Abstract #1160

Validation of Real time Virtual Sonography (RVS) for targeted MR-ultrasound guided transrectal prostate biopsies against transperineal template saturation biopsies for service development

Victoria Sherwood 1 , Donald MacDonald 2 , James Harding 3 , Nicholas Hedley 3 , Kieran Jefferson 2 , Chris Koller 1 , and Charles Hutchinson 3

1 Department of Radiology Physics, University Hospitals Coventry & Warwickshire NHS Trust, Coventry, Warwickshire, United Kingdom, 2 Department of Urology, University Hospitals Coventry & Warwickshire NHS Trust, Coventry, Warwickshire, United Kingdom, 3 Department of Radiology, University Hospitals Coventry & Warwickshire NHS Trust, Coventry, Warwickshire, United Kingdom

A clinical development study was designed to validate targeted MR-ultrasound fusion-guided prostate biopsies against transperineal template saturation biopsies, using Real-time Virtual Sonography (RVS). Twenty-seven patients underwent fusion and template biopsies. Results were compared and related back to multiparametric MRI. Eleven of 19 patients with Gleason 6 disease or above, as diagnosed by template biopsy, tested positive on fusion biopsy. Almost all the remaining patients had Gleason 6 disease, which may not be detected on MRI. RVS has the potential to reduce patient complications and lighten the burden on healthcare services by significantly limiting the number of necessary template saturation biopsies.

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