Abstract #1263
Diffusion-weighted thermometry using subarachnoid space cerebrospinal fluid in subacute carbon monoxide poisoning patients
Shunrou Fujiwara 1 , Yoshichika Yoshioka 2 , Tsuyoshi Matsuda 3 , Hideaki Nishimoto 1 , Toshiyuki Murakami 1 , Akira Ogawa 1 , Kuniaki Ogasawara 1 , Makoto Sasaki 4 , and Takaaki Beppu 1,5
1
Department of Neurosurgery, Iwate Medical
University, Morioka, Iwate, Japan,
2
WPI
Immunology Frontier Research Center, Osaka University,
Suita, Osaka, Japan,
3
MR
Applications and Workflow Asia Pacific, GE Healthcare
Japan, Tokyo, Japan,
4
Division
of Ultrahigh Field MRI, Institu, Iwate Medical
University, Yahaba, Iwate, Japan,
5
Hyperbaric
Medicine, Iwate Medical University, Morioka, Iwate,
Japan
We investigate the potential of cerebrospinal fluid
(CSF) based DWI-thermometry measured in the subarachnoid
space, where the CSF flow quietly changes comparing with
the lateral ventricle, to estimate brain temperature
(BT) in subacute carbon monoxide (CO) poisoned patients
who show the strong imbalance between perfusion and
metabolism in the brain. Our results suggested that the
higher BT measured in the subarachnoid space by DWI than
that measured in white matter by MRS might substantially
reflect the brain metabolism in the subacute CO-poisoned
patients because the CSF in the subarachnoid space
directly lies on the cortex.
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