Meeting Banner
Abstract #1287

Altered tract integrity of the social communication network and its functional correlations in high-functioning autism: a diffusion spectrum imaging (DSI) study

Yu-Chun Lo 1 , Yu-Jen Chen 1 , Yung-Chin Hsu 1 , Susan Shur-Fen Gau 2,3 , and Wen-Yih Isaac Tseng 1,4

1 Center for Optoelectronic Medicine, National Taiwan University College of Medicine, Taipei, Taiwan, 2 National Taiwan University College of Medicine, Department of Psychiatry, Taipei, Taiwan, 3 Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan, 4 Molecular Imaging Center, National Taiwan University, Taipei, Taiwan

Impaired performance in social communication has been consistently found in autism spectrum disorder (ASD). We used diffusion spectrum imaging to measure white matter property of the social communication network, and investigated its relationships with social communication and social awareness for 56 ASD and 44 neurotypicals. ASD showed reduced white matter integrity of the social communication network as compared to neurotypicals. Unique correlations were found between white matter integrity and the social communication ability in ASD. Our results indicate altered functional and structural roles of cores of the social communication network in ASD.

This abstract and the presentation materials are available to members only; a login is required.

Join Here