Accelerated 2D J -Resolved MRS through Non-Uniform Sampling and Iterative Soft Thresholding
Andrew Prescot 1 , Xianfeng Shi 2 , and Perry Renshaw 2,3
Department of Radiology, University of Utah,
Salt Lake City, UT, United States,
of Psychiatry, University of Utah, Salt Lake City, UT,
19 MIRECC, Salt Lake City, UT, United States
Two-dimensional (2D) proton (
resonance spectroscopy (MRS) techniques effectively
enhance spectral resolution by separating metabolite
resonances over a 2D surface. However, full uniform
sampling (FUS) of the indirectly detected frequency
dimension requires long measurement times thus rendering
the methods unsuitable for many clinical applications.
The present work investigates the combination of
non-uniform sampling (NUS) strategies and iterative soft
thresholding to reduce measurement times associated with
MRS data acquired from human brain. A quantitative
assessment of FUS and NUS situations is presented, and
our preliminary data suggests that total measurement
time can be reduced to 25%.
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