Abstract #1313
T 2 estimation of downfield metabolites in human brain at 7T
Nicole D. Fichtner 1,2 , Anke Henning 2,3 , Niklaus Zoelch 2 , Chris Boesch 1 , and Roland Kreis 1
1
Depts. Radiology and Clinical Research,
University Bern, Bern, Switzerland,
2
Institute
for Biomedical Engineering, UZH and ETH Zurich, Zurich,
Switzerland,
3
Max
Planck Institute for Biological Cybernetics, Tuebingen,
Germany
The upfield part of the spectrum has thus far been
well-characterized using magnetic resonance
spectroscopy; however, the downfield part at 5-10ppm
remains less so, particularly in humans. This work aims
to improve metabolite characterization by calculating
the T
2
s of peaks downfield in grey matter at
7 T. We fitted downfield spectra to a heuristic model
and obtained T
2
s for several peaks of
interest; the T
2
s are all fairly similar,
but significantly shorter than those reported for
upfield peaks in the brain, which are approximately 70ms
or longer depending on the structure.
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