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Abstract #1329

Age-Related Changes in Default Mode Sub-Networks

Xueli Wang 1 , Jin Xu 1 , XiuFen Zhang 1 , Xiaolong Peng 1 , and Pan Lin 1

1 Institute of Biomedical Engineering, Xi'an Jiaotong University, Xi'an, Shaanxi, China

Default mode network(DMN) plays an important role in neural cognitive research. Previous studies have suggested that functional connectivity of DMN will decrease with age, which may also cause cognitive decline. However, there is still lack of studies on age-related changes in default mode sub-networks such as anterior default mode network (aDMN) and posterior default mode network (pDMN). The aim of this study was to investigate the age-related effects on functional connectivity between aDMN and pDMN during resting state.

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