Robust 3D MRI of the Mouse Lung Using ZTE Imaging with Background Correction
Markus Weiger 1 , Mingming Wu 1,2 , Moritz Christoph Wurnig 3 , David Kenkel 3 , Wolfgang Jungraithmayr 4 , Andreas Boss 3 , and Klaas Paul Pruessmann 1
Institute for Biomedical Engineering,
University and ETH Zurich, Zurich, Switzerland,
of Biomedical Engineering, Karlsruhe Institute of
Technology, Karlsruhe, Germany,
Diagnostic and Interventional Radiology, University
Hospital Zurich, Zurich, Switzerland,
of Thoracic Surgery, University Hospital Zurich, Zurich,
Zero echo time (ZTE) imaging enables efficient 3D MRI of
tissues with rapid relaxation, such as e.g. the lung.
However, signal is also detected from nearby hardware
parts, e.g. the RF coil, which can lead to substantial
image background. Here, a subtraction method is proposed
to reduce this background to a negligible level. The
technique is applied to pulmonary MRI in the mouse,
providing reproducible results of high quality.
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