Comparing Pulmonary MRI using Inert Fluorinated Gases and Hyperpolarized 3 He: Is 19 F MRI Good Enough?
Marcus J. Couch 1,2 , Iain K. Ball 2 , Tao Li 2 , Matthew S. Fox 3,4 , Birubi Biman 5,6 , and Mitchell S. Albert 1,2
Lakehead University, Thunder Bay, Ontario,
Bay Regional Research Institute, Thunder Bay, Ontario,
Research Institute, London, Ontario, Canada,
of Medical Biophysics, Western University, London,
Bay Regional Health Sciences Centre, Thunder Bay,
Ontario School of Medicine, Thunder Bay, Ontario, Canada
F MRI of the lungs is a new pulmonary
imaging modality that uses inhaled inert fluorinated
gases as a signal source to acquire images of the lungs.
The purpose of this study was to perform a direct
comparison between inert fluorinated gas and
MR lung imaging in the same subjects. This preliminary
study demonstrates the potential of using inert
fluorinated gas MRI to visualize the distribution of
ventilation in human lungs, and this technique may yield
meaningful functional information that is similar to
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