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Abstract #1584

Urinary 1 H NMR-based Metabolomics can Distinguish Sub-fertility Buffalo Bulls

Virendra Kumar 1 , Pawan Kumar 1 , Khushpreet Singh 2 , N R Jagannaathan 1 , and Ajeet Kumar 2

1 Department of NMR, All India Institute of Medical Sciences, New Delhi, Delhi, India, 2 Department of Veterinary Gynaecology and Obstetrics, College of Veterinary Science, GADVASU, Ludhiana, Punjab, India

Sub-fertility in bulls is a major problem and results into huge economic loss. Identification of potential metabolic biomarkers to determine the fertility at earlier developmental stage accurately is important. In present study we used 1 H NMR-based metabolomics to investigate the metabolic profile differences in urine samples to differentiate between buffalo bulls of good fertility and poor fertility. The results of the PLS-DA revealed that sub-fertile bulls be differentiated from fertile bulls based on altered urinary metabolic profiles. Further analysis will be carried out to identify potential metabolic biomarkers which could be used for fertility assessment.

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