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Abstract #1636

DCE-MRI Permeability Analysis in Focused Ultrasound-induced BloodBrain Barrier Opening: the Association with Mechanical Index

Wen Yen Chai 1,2 , Po Chun Chu 2 , Chih Hung Tsai 2 , and Hao Li Liu 2

1 Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Guishan, Taoyuan, Taiwan, 2 Department of Electrical Engineering, Chang Gung University, Guishan, Taoyuan, Taiwan

Two different frequency focus ultrasound exposures were used to induce BBB opening in this study. BBB opening kinetics can be evaluated via dynamic contrast-enhanced MRI (DCE-MRI) and the correlation between MI and the kinetic change will be investigated.

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