Abstract #1649
In vivo chemical shift-compensated MR thermometry
Pooja Gaur 1,2 , Beat Werner 3 , Pejman Ghanouni 4 , Rachelle Bitton 4 , Kim Butts Pauly 4 , and William A Grissom 2,5
1
Chemical and Physical Biology, Vanderbilt
University, Nashville, TN, United States,
2
Institute
of Imaging Science, Vanderbilt University, Nashville,
TN, United States,
3
Center
for MR-Research, University Children's Hospital, Zurich,
Switzerland,
4
Radiology,
Stanford University, Stanford, CA, United States,
5
Biomedical
Engineering, Vanderbilt University, Nashville, TN,
United States
MR thermometry measurements used during thermal
treatments such as focused ultrasound are subject to
heat-induced chemical shift (CS) distortions, which
cause errors in images and temperature maps if left
uncorrected. A CS-correction method has been previously
demonstrated in simulation and phantom studies. In this
work, we apply the method to data from clinical
sonications in the brain and in soft tissue tumors in
the leg. Results show that CS temperature errors can be
reliably corrected in patient data, in 0.6 s per map,
suggesting that corrections could be performed during
the time of treatment.
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