Empirical investigation of tools and imaging techniques for MRI-guided radiotherapy of lung cancer
Tatsuya J Arai 1 , Joris Nofiele 2 , Yam Ki Cheung 1 , Rajiv Chopra 2 , and Amit Sawant 1
Radiation Oncology, UT Southwestern Medical
Center, Dallas, Texas, United States,
UT Southwestern Medical Center, Dallas, Texas, United
Respiratory motion management during the
thoracoabdominal tumor treatment is one of the biggest
challenges in modern image-guided radiation therapy (RT).
MRI enables the long-term, dose-free, soft-tissue
monitoring, representing clear advantages over
x-ray-based imaging modalities. Given unique
requirements of RT guidance-quality (high temporal
resolution, and modest spatial resolution and SNR), we
have been investigating the adaptation of k-t BLAST. We
have also developed MRI-compatible, programmable, and
externally and internally deformable lung motion
phantom, which replicates respiratory motion traces
acquired from lung cancer patients. To our knowledge,
this is the first report of using k-t BLAST for lung
cancer radiotherapy motion management.
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