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Abstract #1677

Inversion Group (IG) Fitting: A New Fitting Algorithm for Modified Look-Locker Inversion Recovery (MOLLI) that allows for Arbitrary Inversion Groupings

Issac Y Yang 1 , Kai-Ho Fok 1 , Bernd J Wintersperger 2,3 , and Marshall S Sussman 2,3

1 Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada, 2 Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada, 3 Joint Department of Medican Imaging, University Health Network & Mt. Sinai Hospital, Toronto, Ontario, Canada

Modified Look-Locker Inversion Recovery (MOLLI) is a common technique for T1 mapping of the heart. However, it requires a lengthy rest period in between inversion groupings to allow for complete magnetization recovery. A new MOLLI fitting algorithm with a new fitting model is presented in this work to allow for arbitrary inversion groupings and rest periods, including no rest period. Phantom and in-vivo experiments verified the technique. T1 values measured using several different inversion grouping/rest period combinations yielded consistent results with the new algorithm, but with a slight loss of precision.

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