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Abstract #1717

Inference at the cluster level from the relationship between QSM and age

Julio Acosta-Cabronero 1 , Arturo Cardenas-Blanco 1 , and Peter J Nestor 1

1 German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Saxony-Anhalt, Germany

This study explores, with relatively unbiased methods, the relationship between increased paramagnetism in brain parenchyma and age. Brain magnetostatics was probed with quantitative susceptibility mapping (QSM) revealing strong striatal effects as a function of age. In addition, QSM clusters in the diencephalon, mesencephalonand in a more patchy distribution, across the cerebral cortex and posterior white matteralso emerged as age-related effects.

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