Disentangling different Gadolinium concentrations: a comparison between High Field and Very Low Field MRI.
Allegra Conti 1 , Massimo Caulo 1,2 , Angelo Galante 3 , Vittorio Pizzella 1,2 , Gian Luca Romani 1,2 , and Stefania Della Penna 1,2
Department of Neuroscience, Imaging and
Clinical Sciences, G. D'Annunzio Univ. of Chieti and
Pescara, Chieti, CH, Italy,
for Advanced Biomedical Technologies (ITAB), G.
D'Annunzio Univ. of Chieti and Pescara, Chieti, CH,
Department of Life, Health & Environmental Sciences,
L'Aquila University, L'Aquila, AQ, Italy
Gadolinium based Contrast Agents are routinely used in
MRI to improve the diagnostic accuracy of brain
pathologies. Recently, Very and Ultra Low Field-MRI
scanners have been developed, and the advantages of
these system in the study of tissue contrast have been
suggested. Here we show how the contrast of T1-weighted
images of different concentrations of MultiHance and
Gadovist changes varying the applied field (8.9 mT, 0.2
T, 1. 5 T ,3 T). Results demonstrate that signal
contrast does not improve at high field strengths, and
that longitudinal relaxation rate-maps at ULF are the
best instruments to distinguish different
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