Abstract #2018
Efficient Spectroscopic Imaging by an Optimized Encoding of pre-Targeted Brain Main Metabolic Resonances
Zhiyong Zhang 1,2 , Noam Shemesh 1,3 , and Lucio Frydman 1
1
Chemical Physics Department, Weizmann
Institute of Science, Rehovot, Israel,
2
Department
of Electronic Science, Xiamen University, Xiamen,
Fujian, China,
3
Champalimaud
Neuroscience Programme, Champalimaud Centre for the
Unknown, Lisbon, Portugal
Recently, a relaxation-enhanced (RE)
selective-excitation MRS approach to acquire
in
vivo
localized
spectra with flat baselines and very good
signal-to-noise ratios (SNR) has been proposed. As RE
MRS targets
a
priori
known
resonances, MRSI information may be acquired in a
faster, more efficient manner. Hereby we present such
Relaxation-Enhanced Chemical-shift-Encoded
Spectroscopically-Separated (RECESS) MRI method,
targeting images of various metabolite by collecting a
series of conventional imaging data echoes where the
chemical shifts of the different resonances are encoded
by coherent phase modulations, and disentangled by
Fourier-based inversions. The RECESS method thus
accelerates the acquisition of quality MRSI data.
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