Abstract #2110
Simultaneous acquisition of structural and resting state functional connectivity data using a volumetric navigated diffusion sequence
Mwape Mofya 1 , Alkatafi Ali Alhamud 1 , Paul A. Taylor 1,2 , Andr J. W. van der Kouwe 3 , and Ernesta M. Meintjes 1
1
MRC/UCT Medical Imaging Research Unit,
Department of Human Biology, University of Cape Town,
Cape Town, South Africa,
2
African
Institute for Mathematical Sciences (AIMS), South
Africa,
3
Massachusetts
General Hospital, Boston, Massachusetts, United States
Simultaneous DTI-fMRI data collection has previously
been unsuccessful, due to mutual interference of the
acquired DTI and fMRI signals. In this work, a single 3D
EPI navigator, which has been used for motion correction
and shown not to interfere with DWI collection, has been
inserted after each DWI volume for BOLD measurement. For
faster temporal sampling, we also test the inclusion of
a second 3D EPI navigator in the middle of each DTI
volume acquisition. Resting state networks produced in
the standard BOLD and double navigated DTI-fMRI showed
quite similar spatial extent and connectivity. Diffusion
data produced similar whole brain distributions of
tensor parameters, as well as strikingly similar
tractographic reconstructions.
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