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Abstract #2120

Bold Oxygen Level Dependant (BOLD) Quantitative Susceptibility Mapping (QSM) at Different Head Orientations

M Ethan MacDonald 1,2 , Avery Berman 2,3 , Rebecca J Williams 1,2 , Erin L Mazerolle 1,2 , and G Bruce Pike 1,2

1 Radiology and Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada, 2 Hotchkiss Brain Institute, Foothills Medical Centre, Alberta Health Services, Calgary, Alberta, Canada, 3 Biomedical Engineering, McGill University, Montreal, Quebec, Canada

In this work, we use a quantitative susceptibility technique calculated from the phase data from BOLD-fMRI. Measurements of the susceptibility time course (BOLD-QSM) are compared to BOLD-fMRI in visual and motor regions. Subjects heads are moved and imaging is repeated. Contrast to noise ratio is calculated in the signals from both techniques and found to be comparable. Five of eight measured signals showed higher CNR with the BOLD-QSM method. A good level of correlation is obtained between the two methods.

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