Investigating the effect of hyperoxia and hypercapnia on T2* and S0 calculated from multi-echo BOLD data at 7T.
Alex A Bhogal 1 , Jeroen C.W. Siero 2 , Marielle E. Philippens 2 , Esben T. Petersen 2 , Martijn Froeling 2 , Jeroen Hendrikse 2 , Manus J. Donahue 3 , and Hans Hoogduin 2
University Medical Center, Utrecht, Utrecht,
Medical Center, Utrecht, Netherlands,
University School of Medicine, Tennessee, United States
Hypercapnia and hyperoxia, induced using targeted gas
challenges, may be used to probe physiological effects
related to the Blood Oxygen Level Dependent (BOLD)
signal. Multi-echo BOLD data is acquired allowing
changes in T2* and S0 parameters in response to
breathing challenges to be examined. Results are
explained in the context of physiological phenomenon.
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