Abstract #2136
Investigation of neurovascular coupling within brain by simultaneous recordings of LFP and fiber-optic hemodynamic signals
Wen-Ju Pan 1 , Jacob Billings 1 , and Shella Keilholz 1
1
Biomedical Engineering, Emory University/
Georgia Institute of Technology, Atlanta, Georgia,
United States
Intrinsic optical spectroscopy (IOS) may provide
multiple hemodynamic parameters in high time resolution
in functional optical imaging but rarely used within
brain study. We developed a combination of optic
fiber-based IOS, ~100um in diameter, and microelectrode
neuronal LFP signal recording within brain at similar
spatial range, a few hundred micros. This simultaneous
recording design may be a promising approach for
examining target sites of neurovascular coupling
relations in brain.
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