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Abstract #2239

Volumetric MRSI as a tool to guide and monitor radiotherapy treatment in patients with glioma

Anouk Marsman 1 , Sulaiman Sheriff 2 , Doris D. Lin 1 , Andrew A. Maudsley 2 , Lawrence Kleinberg 3 , and Peter B. Barker 1

1 Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States, 2 Department of Radiology, University of Miami Miller School of Medicine, Miami, Florida, United States, 3 Department of Radiation Oncology & Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States

Volumetric echo-planar spectroscopic imaging (EPSI) is a promising technique for mapping human brain tumors, based on elevated lesion choline (Cho) signals. This abstract reports the results of an interim analysis of an on-going project to determine if post-surgical EPSI has a role in radiotherapy planning in subjects with high-grade glioma, as well as to investigate the effects of treatment on tumor metabolism.

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