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Abstract #2278

Diagnostic Performance of Dynamic Susceptibility Contrast Perfusion in Glioma Grading: Comparison of Cerebral Blood Volume among Different Analysis Software

Kohsuke Kudo 1 , Ikuko Uwano 2 , Toshinori Hirai 3 , Hideo Nakamura 4 , Noriyuki Fujima 1 , Fumio Yamashita 2 , Jonathan Goodwin 2 , Satomi Higuchi 2 , and Makoto Sasaki 2

1 Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sapporo, Hokkaido, Japan, 2 Ultra-High Field MRI, Iwate Medical University, Morioka, Japan, 3 Radiology, Kumamoto University, Kumamoto, Japan, 4 Neurosurgery, Kumamoto University, Kumamoto, Japan

The purpose of the present study was to compare rCBV value of DSC perfusion and diagnostic performance of rCBV for discriminating low grade and high grade tumor among different software packages in patients with cerebral glioma. CBV maps were generated by 11 different algorithms of four commercially available software and one academic program. Diagnostic performances of rCBV for glioma grading were not statistically significant among post-processing software. However, rCBV values and cut off values for discriminating low grade and high grade gliomas were different among algorithms.

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