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Abstract #2352

Comparison of 3 and 7 Tesla arterial spin labelling techniques for simultaneous functional perfusion and BOLD MRI studies

Dimo Ivanov 1 , Anna Gardumi 1 , Benedikt A Poser 1 , Josef Pfeuffer 2 , and Kmil Uluda─č 1

1 Department of Cognitive Neuroscience, Maastricht University, Maastricht, Netherlands, 2 Application Development, Siemens Healthcare, Erlangen, Germany

In this study, a pCASL and two PASL variants at 3 T are compared with a PASL approach at 7 T to determine, which of the techniques is most suited for simultaneous high temporal resolution functional CBF and BOLD measurements. The 3 T techniques show no significant differences in either grey matter perfusion or temporal SNR values. In contrast, the 7 T variant tested delivers significantly lower grey matter CBF and temporal SNR values, while offering improved BOLD sensitivity. This indicates that further technical improvements might be necessary for 7 T ASL to be able to reach its full potential.

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