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Abstract #2354

Quantifying Cerebral Blood Flow: A Comparison of Two Non-invasive Perfusion Imaging Techniques

Gena Matta 1,2 , Andrew D Robertson 1 , Sandra E Black 1,3 , and Bradley J MacIntosh 1,3

1 Canadian Partnership for Stroke Recovery, Sunnybrook Research Institute, Toronto, Ontario, Canada, 2 University of Waterloo, Waterloo, Ontario, Canada, 3 University of Toronto, Toronto, Ontario, Canada

Arterial-spin labelling (ASL) and phase-contrast angiography (PCA) provide two non-invasive methods to quantify the total cerebral blood flow. The primary aim of this study was to assess the agreement of CBF ASL and CBF PCA in two cerebrovascular cohorts: overt stroke and small vessel diseases (SVD), and to (2) assess the repeatability of each technique within a stroke cohort. We observed significant differences between the total CBF estimates produced by each modality, therefore we state that caution is warranted when comparing total CBF between modalities among patients with cerebrovascular disease. Intra-subject repeatability was high, however, for both approaches.

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