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Abstract #2453

CAIPIRINHA acceleration enables rapid high-spatial-resolution isotropic 3D SPACE of the knee: Comparison with conventional SPACE and 2D TSE

Esther Raithel 1 , Gaurav Thawait 2 , Shivani Ahlawat 2 , Shadpour Demehri 2 , Zhang Qiong 3 , and Jan Fritz 2

1 Siemens AG, Healthcare Sector, Erlangen, Bavaria, Germany, 2 Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Maryland, United States, 3 Siemens AG, Guang Dong, China

While 2D TSE MRI is standard in musculoskeletal MRI, similar performance was shown for 3D TSE-type sequences (SPACE) before; however, long acquisition times may limit its clinical use. In contrast to one-dimensional acceleration, a 2x2 CAIPIRINHA pattern can yield substantial acceleration of 3D data acquisition. We demonstrate the implementation of a 4-fold CAIPIRINHA acceleration pattern into a 3D SPACE sequence with a resultant 50-60% decrease of the acquisition time when compared to a standard 2-fold accelerated SPACE. A 5-min CAIPIRINHA SPACE sequence can produce near identical image quality in the knee as 11-min SPACE and 10-min three plane 2D TSE sequences.

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