Abstract #2464
In-vivo High Resolution Imaging of Fine-Scale Anatomical Structures at 3T with Simultaneous Bias/Variance Reduction
Aymeric Stamm 1 , Onur Afacan 2 , Benoit Scherrer 2 , Jolene M Singh 1 , and Simon K Warfield 1
1
Computational Radiology Laboratory,
Department of Radiology, Boston Children's Hospital,
Harvard Medical School, Boston, MA, United States,
2
Boston
Children's Hospital, Harvard Medical School, Boston, MA,
United States
High resolution imaging has an important role to play in
the detection of malformations of cortical development,
and can dramatically improve the prospect of a surgical
cure in epilepsy, or in the detection of brain lesions.
We propose a novel, unified reconstruction strategy that
overcomes prior limitations and show that the strategy
can be applied to imaging the stria of Gennari in vivo
in a reasonable amount of time on a conventional 3T
magnet. Our proposed technology enables image
reconstruction from inter-session and intra-session
k-space data, that overcomes intra-session and
inter-session phase variation to enable arbitrarily high
SNR imaging.
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