Partial Volume Correction based on Spatial Variant Point Spread Function for Simultaneous PET-MR Imaging
Chenguang Peng 1 , Jinchao Wu 1 , Xingfeng Shao 1,2 , Yingmao Chen 3 , Quanzheng Li 4 , Georges El Fakhr 4 , and Kui Ying 1
Key Laboratory of Particle and Radiation
Imaging, Ministry of Education, Department of
Engineering, Beijing, China,
of Bioengineering, UCLA, California, United States,
of Nuclear Medicine, The general hospital of Chinese
People's Liberation, Beijing, China, Beijing, China,
of Radiology, Division of Nuclear Medicine and Molecular
Imaging, Harvard Medical School, Boston, United States
PET image has relatively low resolution, and partial
volume effect (PVE) is one of the major reason for this.
Hybrid PET-MRI system offers us a great opportunity to
synthesis PET and MRI, and MRI can provide PET with high
resolution anatomical image which is a great
supplementary information to correct PVE. In traditional
method, point spread function is usually used to
described PVE and is regarded as a spatial invariant
constant which is not true in real PET system. In this
work, we proposed a new method that considered spatial
variant point spread function.
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