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Abstract #2499

Efficient Dictionary Design for MR Fingerprinting using Tree-Structured Vector Quantization

Zhitao Li 1 , Benjamin Paul Berman 2 , Diego R Martin 3 , Maria I Altbach 3 , and Ali Bilgin 1,4

1 Electrical and Computer Engineering, University of Arizona, Tucson, Arizona, United States, 2 Applied Mathematics, University of Arizona, Tucson, Arizona, United States, 3 Department of Medical Imaging, University of Arizona, Tucson, Arizona, United States, 4 Biomedical Engineering, University of Arizona, Tucson, Arizona, United States

Accurate parameter estimation in MR Fingerprinting (MRF) requires large dictionaries with many atoms, each with thousands of time points. Storage of such dictionaries require large memory and the matching process becomes increasingly demanding with increasing dictionary size. We propose a Tree Structured Vector Quantizer based clustering approach for MRF dictionary design. The proposed approach allows significant reduction in dictionary dimensions and can enable clinically relevant reconstruction accuracy and time which is a major bottleneck for clinical usefulness of MRF.

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