Abstract #2529
Validation of Waveguide Magnetic Resonance Elastography Using Finite Element Model Simulation
Ria Mazumder 1,2 , Renee Miller 3 , Haodan Jiang 4 , Bradley D. Clymer 1 , Richard D. White 2,5 , Alistair Young 3 , Anthony Romano 6 , and Arunark Kolipaka 2,5
1
Department of Electrical and Computer
Engineering, The Ohio State University, Columbus, OH,
United States,
2
Department
of Radiology, The Ohio State University College of
Medicine, Columbus, OH, United States,
3
Department
of Anatomy with Radiology, The University of Auckland,
New Zealand,
4
Department
of Research and Development, Ohio Supercomputer Center,
OH, United States,
5
Department
of Internal Medicine-Division of Cardiology, The Ohio
State University College of Medicine, OH, United States,
6
Naval
Research Laboratory, DC, United States
Anisotropic mechanical properties of tissues vary in
response to different pathological conditions; hence,
the development of a technique for non-invasive
anisotropic stiffness quantification is expected to have
diagnostic and prognostic significance. Recently,
waveguide magnetic resonance elastography (MRE) has been
used to non-invasively estimate anisotropic stiffness of
biological tissues by measuring tissue deformation as a
result of external perturbation in directions specified
by fiber orientation. In this study, we simulate fibers
using finite element modeling in a cylindrical rod to
validate the stiffness measurements obtained using
waveguide MRE. Our results show that the technique can
successfully estimate anisotropic stiffness in an
orthotropic material.
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