In vivo rapid 3D Microscopic DTI combining Super Resolution Reconstruction and Reverse Gradient correction method
Ulysse Gimenez 1 , Antoine Triquet 1 , and Hana Lahrech 1
Clinatec, CEA, Grenoble, Rhones-Alpes,
Super Resolution Reconstruction is performed on 2D EPI
distorted diffusion images acquired in vivo on brain
mouse at 9.4T. At this field, the feasibility to correct
severe distortions with Reverse Gradient method is
proved. Based on three orthogonal low resolution DTI
acquisition (120*120*360 m3), SRR is successfully
performed allowing the calculation of 3D isotropic high
spatial resolution DTI (120*120*120 m3). Thus, high
spatial resolution DTI parameter maps can be visualized.
Fibertracking is also computed and fine white matter
structures such as the fornix can be rebuilt.
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