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Abstract #2576

Quantification of Fetal Motion Tracked with Volumetric Navigator MRI Acquisitions

Patrick McDaniel 1 , Borjan Gagoski 2 , M. Dylan Tisdall 3,4 , Andr J. W. van der Kouwe 3,4 , P. Ellen Grant 2,4 , Lawrence Wald 3,4 , and Elfar Adalsteinsson 1,5

1 Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States, 2 Fetal-Neonatal Neuroimaging and Developmental Science Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States, 3 Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, United States, 4 Radiology, Massachusetts General Hopsital, Boston, MA, United States, 5 Health Sciences and Technology, Harvard-MIT, Cambridge, MA, United States

The ability to perform higher quality fetal brain imaging would be facilitated by navigators that track fetal head motion. We demonstrate the feasibility of measuring this motion along six degrees of freedom using 3D volumetric navigator (vNav) acquisitions. A series of vNavs is acquired over time, and a fetal head ROI is identified within the first 3D volume to serve as a template for rigid-body registration of subsequent 3D images. Registrations are performed with FSL FLIRT, producing affine transformation matrices which provide quantitative measurements of fetal head displacement and rotation.

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