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Abstract #2584

Comparison of High Resolution LGE and High Resolution Electro-Anatomical Mapping for Imaging of the Ventricular Arrhythmia Substrate in a Swine Model of Ventricular Tachycardia

Sbastien Roujol 1 , Tamer A. Basha 1 , Cory Tschabrunn 1 , Kraig V. Kissinger 1 , Warren J. Manning 1,2 , Mark E. Josephson 1 , Elad Anter 1 , and Reza Nezafat 1

1 Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States, 2 Department of Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States

ICD therapy is the first line therapy for the prevention of sudden cardiac death. Reduced incidence of ICD therapy can be achieved when combined with catheter based ventricular tachycardia (VT) ablation in patient with history of myocardial infarction. However, the recurrence rate of VT/VF after VT ablation is about ~50% in these patients and better technique for VT substrate identification are needed. Late gadolinium enhancement (LGE) CMR has the potential for non-invasive assessment of the VT substrate, which consists of reentry circuits near or within a chronic scar. In this study, we sought to utilize a high-resolution 3D LGE sequence with 1 mm3 isotropic spatial resolution to image a surrogate of the VT substrate in swine model of VT.

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