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Abstract #2605

Cardiovascular Magnetic Resonance T2-STIR Imaging is Unable to Discriminate Between Intramyocardial Haemorrhage and Microvascular Obstruction

Esben Svs Szocska Hansen 1,2 , Steen Fjord Pedersen 3 , Steen Bnnelykke Pedersen 4 , Uffe Kjrgaard 1 , Nikolaj Hjort Schmidt 5 , Hans Erik Btker 6 , and Won Yong Kim 1,6

1 The MR Research Centre, Aarhus University, Skejby, Aarhus, Denmark, 2 Danish Diabetes Academy, Odense, Denmark, 3 Dept. of Cardiothoracic and Vascular Surgery T, Aarhus University Hospital Skejby, Skejby, Aarhus N, Denmark, 4 Dept. of Department of Endocrinology and Internal Medicine, Aarhus University Hospital THG, Skejby, Aarhus, Denmark, 5 Department of Clinical Medicine - Comparative Medicine Laboratory, Aarhus University, Skejby, Aarhus, Denmark, 6 Dept. of Cardiology, Aarhus University Hospital Skejby, Skejby, Aarhus, Denmark

Recent studies have used cardiovascular magnetic resonance (CMR) and T2-weighted short tau inversion recovery (T2-STIR) imaging to detect intramyocardial haemorrhage (IMH) as a measure of ischemic/reperfusion injury. We investigated the ability of T2-STIR to differentiate between microvascular obstruction (MVO) and IMH in an experimental pig model of ischemic/reperfusion injury. T2-STIR results were validated by histopathology showing a sensitivity of 100% and specificity of 29% respectively, for detection of IMH. T2-mapping showed no significant difference between T2 values from areas with MVO versus MVO and IMH. In conclusion, T2-STIR was unable to differentiate between IMH and MVO in myocardial ischemic/reperfusion injury.

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