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Abstract #2620

Non-contrast characterization of interstitial cardiac remodeling in chronic kidney disease patients

Tori A Stromp 1 , Steve W Leung 2,3 , Vincent L Sorrell 2,3 , and Moriel H Vandsburger 1,2

1 Department of Physiology, University of Kentucky, Lexington, KY, United States, 2 Saha Cardiovascular Research Center, University of Kentucky, Lexington, Kentucky, United States, 3 Gill Heart Institute, University of Kentucky, Lexington, KY, United States

Patients with chronic kidney disease are at high risk for adverse cardiac events with an emerging link to fibrosis. While such patients would benefit from diagnosis with LGE, they are contraindicated due to safety concerns. We compared two methods of non-contrast cardiac MRI to identify interstitial remodeling in a patient population on routine hemodialysis for CKD. Both native T1 mapping and our previously developed cine bSSFP method (termed 2-point bSSFP) showed greater enhancement patterns in patients with CKD compared to healthy controls, indicating areas of interstital remodeling.

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