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Abstract #2634

Preliminary Rat Myocardial Tissue Characterisation at 4.7T

Matthew Firth 1 , Marco Mingarelli 1 , Hugh Seton 1 , and Dana Dawson 1

1 University of Aberdeen, Aberdeen, United Kingdom

In-vivo MRI was carried out on four healthy rats at 4.7 T to obtain a series of T2* measurements in the heart septum. A prospectively gated gradient echo pulse sequence was used with TE values covering the range 5-30 ms. The results were combined to provide a normal dataset for future comparison with rat studies of iron overload cardiomyopathy or cardiac contrast agents. The mean T2* value was 10.12 4.40 ms. We discuss measures that could be taken to improve SNR and reduce signal variation in prospectively gated studies.

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