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Abstract #2639

In Vivo Spin Echo EPI Cardiac Diffusion Tensor MRI Using Ultrahigh Gradient Amplitudes

Eric Aliotta 1,2 , Stanislas Rapacchi 1 , Peng Hu 1 , and Daniel Ennis 1,2

1 Radiological Sciences, UCLA, Los Angeles, CA, United States, 2 Biomedical Physics IDP, UCLA, Los Angeles, CA, United States

The purpose was to improve the robustness to bulk motion of spin-echo (SE) cardiac diffusion tensor MRI (DTI) by using ultrahigh maximum gradient amplitudes (Gmax=80mT/m, G80) and a biophysical reconstruction constraint algorithm (BRCA). We found that G80+BRCA offers more accurate ADC and FA quantification and produces a more homogeneous ADC map in accordance with the literature. Shorter diffusion preparation times made possible with ultrahigh gradients combined with a biophysical reconstruction constraint algorithm (BRCA) improved the robustness to bulk motion of cardiac DTI.

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