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Abstract #2652

Assessment of calcification size and juxtaluminal status using gray-blood 3D vessel wall MRI

Niranjan Balu 1 , Jie Sun 1 , Jin Liu 2 , Shuo Chen 3 , Huijun Chen 3 , and Chun Yuan 1

1 Radiology, University of Washington, Seattle, Washington, United States, 2 Bioengineering, University of Washington, Seattle, Washington, United States, 3 CBIR, Tsinghua University, Beijing, China

Large calcification size and juxtaluminal status of calcification may be indicative of high-risk plaque. Calcification assessment using plaque MRI traditionally requires multicontrast MRI including black-blood and bright-blood weightings. We develop a new method using 3D isotropic gray-blood MRI contrast that is acquired simultaneously with image weightings for identifying intraplaque hemorrhage and stenosis. We validate the method against 2D multi-contrast plaque MRI for assessment of calcification size and juxtaluminal/intraplaque calcification status and show that our method provides accurate results comparable to established plaque MRI methods.

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