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Abstract #2842

Line graphs and vector weights: a novel paradigm for brain network analysis

Peter Savadjiev 1 , Carl-Fredrik Westin 2 , and Yogesh Rathi 1

1 Psychiatry Neuroimaging Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States, 2 Laboratory for Mathematics in Imaging, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States

Graph theoretical representations of brain networks model the organization of gray matter units. We introduce a novel Dual graph formalism, in which the role of edges and vertices is inverted relative to the original (Primal) graph. This transformation shifts the emphasis of brain network analysis from gray matter units to their underlying connections. It applies standard graph theoretical operations to discover the organization of connections, as opposed to gray matter centers. Furthermore, it facilitates the characterization of each connection by a vector of several features. This is one solution to the problem of vector weights in standard brain network analysis.

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