A new fiber bundle pathway identified with diffusion MRI fiber tractography: Fact or fantasy?
Anneriet M Heemskerk 1 , Michel Thiebaut de Schotten 2 , Marco Catani 2 , Silvio Sarubbo 3 , Laurent Petit 4 , Max Viergever 1 , Derek K. Jones 5 , John Evans 5 , Tom Paus 6,7 , and Alexander Leemans 1
Image Sciences Institute, University Medical
Center Utrecht, Utrecht, Netherlands,
College London, United Kingdom,
Chiara Hospital, Italy,
CNRS, CEA, University of Bordeaux, Bordeaux, France,
University, United Kingdom,
Research institute, Baycrest, Toronto, Canada,
of Psychology and Psychiatry, University of Toronto,
Diffusion-weighted MRI based fiber tractography (FT) is
widely used and its methodology is constantly improving.
Despite the many pitfalls and limitations of FT, we
present a description of fiber tract pathways in the
orbitofrontal / prefrontal cortex, which to the best
of our knowledge have not been reported before with
FT. A consistent tract configuration across multiple
subjects and different data cohorts was observed which
boost our confidence that this finding is not based on
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