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Abstract #2894

Effects of maximal b value and sampling interval on water displacement profile in q-space imaging

Ping-Huei Tsai 1,2 , Hua-Shan Liu 2,3 , Hsiao-Wen Chung 4 , Chia-Feng Lu 2 , Fei-Ting Hsu 2 , Li-Chun Hsieh 2 , and Cheng-Yu Chen 1,2

1 Department of Radiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, 2 Imaging Research Center and Department of Medical Imaging, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan, 3 Graduate Institute of Clinical Medicine, Taipei Medical University, Taipei, Taiwan, 4 Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan

q-space imaging (QSI) is an advanced diffusion-weighted imaging technique to explore the water displacement profile. The purpose of this study is to assess the effects of maximal b value and sampling interval on water displacement profile in simulation and validate it in clinical application of the brain. Our preliminary finding demonstrated that the proposed sampling pattern provides an alternative to obtain QSI images and reliable MD and ZDP measurements with a shorter acquisition time, which may be helpful in the implementation of in vivo brain q-space imaging in clinical application.

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