Quantitative Evaluation of Rotating Short-Axis (RSA) EPI for High Spatial Resolution Diffusion MRI
Yu-Chien Wu 1
Radiology and Imaging Sciences, Indiana
University School of Medicine, Indianapolis, IN, United
A new sequence, Rotating Short-Axis (RSA) echo-planar
imaging (EPI), may address some issues associated with
single-shot spin-echo EPI sequences for diffusion MRI.
RSA has a higher signal-to-noise ratio due to the
shorter echo time, minimal geometric distortion from
shorter echo spacing, and a faster imaging speed due to
partial k-space sampling. RSA works better in high
spatial resolution diffusion MRI. Here we performed
computer simulations to quantitatively evaluate blade
sampling and composite reconstruction in RSA methods
with respect to effective image resolution, artifacts,
and directional estimates of fiber orientations. The
results were compared with pseudo gold standard,
single-shot spin-echo EPI.
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