Abstract #2903
Influence of blood flow on intracranial water fluctuation: a phantom study
Shota Ishida 1 , Tosiaki Miyati 1 , Naoki Ohno 1 , Tomohiro Chigusa 2 , Hikari Usui 3 , Masaaki Hattori 4 , Yuki Hiramatsu 4 , Satoshi Kobayashi 5 , and Toshifumi Gabata 5
1
Division of Health sciences, Graduate School
of Medical Sciences, Kanazawa University, Kanazawa,
Ishikawa, Japan,
2
Okazaki
City Hospital, Okazaki, Aichi, Japan,
3
Yokohama
City University Hospital, Yokohama, Kanagawa, Japan,
4
School
of Health sciences, College of Medical, Pharmaceutical
and Health sciences, Kanazawa University, Kanazawa,
Ishikawa, Japan,
5
Department
of Radiology, Kanazawa University School of Medicine,
Kanazawa, Ishikawa, Japan
To clarify relations and mechanisms of perfusion and
water fluctuation, we assessed the influence of blood
flow on ADC change in cardiac cycle (delta-ADC) using
original cranial MRI-phantom. With use of low b-values,
both maximum ADC and minimum ADC during the pulsation
period increased with the simulated total cerebral blood
flow. However, with high b-values, minimum ADC did not
increase with the simulated total cerebral blood flow.
Therefore, water fluctuation was predominant with high
b-values. Delta-ADC in combination with high b-values
makes it possible to minimize the direct effect of blood
flow.
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