Abstract #2920
Double-pulsed diffusional kurtosis imaging for the in vivo assessment of human brain microstructure
Edward S. Hui 1 and Jens H. Jensen 2,3
1
Department of Diagnostic Radiology, The
University of Hong Kong, Pokfulam, Hong Kong, China,
2
Department
of Radiology and Radiological Science, Medical
University of South Carolina, Charleston, South
Carolina, United States,
3
Center
for Biomedical Imaging, Medical University of South
Carolina, Charleston, South Carolina, United States
We have recently extended conventional
single-pulsed-field-gradient (s-PFG) DKI to double-PFG
(d-PFG) diffusion MRI sequence, known as double-pulsed
DKI (DP-DKI). Owing to the fact that DKI isolates the
second order contributions to the d-PFG signal, the 6D
diffusional kurtosis encodes unique information beyond
that available from s-PFG sequences. This study
demonstrates the feasibility of in vivo human DP-DKI at
3 T.
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