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Abstract #2935

Reducing slab boundary artifacts in 3D multi-slab diffusion imaging by jointly estimating slab profile and image

Wenchuan Wu 1 , Peter Koopmans 1 , Robert Frost 1 , and Karla L Miller 1

1 FMRIB Centre, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, Oxfordshire, United Kingdom

Several correction methods (e.g. direct combination, PEN) have been proposed to reduce slab boundary artifacts in 3D multi-slab diffusion imaging. However, these methods are only capable of removing aliasing artifacts and require long scan time. In this work, a method compatible with optimal TRs is proposed to reduce slab boundary artifacts by jointly estimating slab profile and image. Initial results show the superior performance of our proposed method over the other two methods.

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