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Abstract #2974

Detection of Brain Activation Using High-Resolution Arterial Spin Labeling Perfusion fMRI at 3T

Iris Asllani 1 , Ajna Borogovac 2 , Dylan Bruening 2 , Sophie Schmid 3 , Wouter M. Teeuwisse 3 , and Matthias J.P. van Osch 3

1 RIT, Rochester, NY, United States, 2 RIT, NY, United States, 3 Leiden University Medical Center, Leiden, Netherlands

We have tested the feasibility of high-resolution (1.15mm x 1.15mm x 3mm) arterial spin labeling (ASL) fMRI for detecting changes in CBF due to motor activation at 3T. The SNR of the high-resolution ASL was compared to that of the commonly used low-resolution ASL, with and without correcting for partial volume effects. Availability of high-resolution CBF imaging should increase the utility of ASL for clinical and neuroscience applications.

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