Choices in processing steps for diffusion MRI analyses: Does it really matter?
Szabolcs David 1 , Chantal M. W. Tax 1 , Max A. Viergever 1 , Anneriet Heemskerk 1 , and Alexander Leemans 1
Image Sciences Institute, University Medical
Center Utrecht, Utrecht, Utrecht, Netherlands
Different implementations of processing steps such as
correction for subject motion and artifacts (e.g., eddy
current induced distortions and susceptibility related
deformations), spatial normalization, and estimation
approach used during diffusion MRI analysis may provide
different results, but whether such potential
differences are significant for a typical tract analysis
remains unknown. In this work, we investigated the
effect of tensor estimation approach and interpolation
strategy on diffusion measures for a tractography based
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