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Abstract #2997

Improving cortical tractography using double inversion recovery

Hamied A Haroon 1 , Claude J Bajada 2 , Hojjatollah Azadbakht 1 , and Sha Zhao 1

1 Centre for Imaging Sciences, The University of Manchester, Manchester, England, United Kingdom, 2 School of Psychological Sciences, The University of Manchester, Manchester, England, United Kingdom

If CSF is not correctly masked out in high angular-resolution diffusion images (HARDI) then tractography can generate spurious and random anatomical connections outside of the brains parenchyma, via voxels containing CSF. We present a method based on double inversion recovery (DIR) to segment and mask out CSF efficiently and improve cortical tractography. DIR data are acquired at the same resolution and geometry as HARDI data, and therefore makes DIR an ideal technique to mask out CSF in HARDI data as they are in the same space and the voxels have the same partial volume effects.

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